GBDR1 rabbit pAb

Products

GBDR1 rabbit pAb

One-click to copy product information

ES2405

Size：	Price：
50 µL	$148.00
100 µL	$248.00

Manual Send email to us

Overview

Product name:	GBDR1 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	UBAC1; GBDR1; KPC2; UBADC1; Ubiquitin-associated domain-containing protein 1; UBA domain-containing protein 1; E3 ubiquitin-protein ligase subunit KPC2; Glialblastoma cell differentiation-related protein 1; Kip1 ubiquitination-promoting com
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	45kD
GeneID:	10422
Human Swiss-Prot No:	Q9BSL1
Cellular localization:	Cytoplasm .
Background:	function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.,tissue specificity:Ubiquitous.,

Western Blot analysis of various cells using GBDR1 Polyclonal Antibody diluted at 1:500
Western blot analysis of lysates from 293 and HUVEC cells, using UBAC1 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HT-29 cells using UBAC1 antibody.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).