| Product name: |
Fyb rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
FYB; SLAP130; FYN-binding protein; Adhesion and degranulation promoting adaptor protein; ADAP; FYB-120/130; p120/p130; FYN-T-binding protein; SLAP-130; SLP-76-associated phosphoprotein |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from Fyb . at AA range: 620-700 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
85kD |
| GeneID: |
2533 |
| Human Swiss-Prot No: |
O15117 |
| Cellular localization: |
Cytoplasm . Nucleus . Cell junction . Colocalizes with TMEM47 at cell-cell contacts in podocytes. . |
| Background: |
The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011], |
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