Products

Fra-1 rabbit pAb
ES2370
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: Fra-1 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: FOSL1; FRA1; Fos-related antigen 1; FRA-1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Fra-1. AA range:101-150
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 43kD
GeneID: 8061
Human Swiss-Prot No: P15407
Cellular localization: Nucleus .
Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],