Product name: | Fra-1 rabbit pAb |
Reactivity: | Human;Mouse;Rat |
Alternative Names: | FOSL1; FRA1; Fos-related antigen 1; FRA-1 |
Source: | Rabbit |
Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human Fra-1. AA range:101-150 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 43kD |
GeneID: | 8061 |
Human Swiss-Prot No: | P15407 |
Cellular localization: | Nucleus . |
Background: | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014], |