Fos B rabbit pAb

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Fos B rabbit pAb

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ES2359

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Fos B rabbit pAb
Reactivity:	Human;Mouse;Monkey
Alternative Names:	FOSB; G0S3; Protein fosB; G0/G1 switch regulatory protein 3
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human FosB. AA range:12-61
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	35kD
GeneID:	2354
Human Swiss-Prot No:	P53539
Cellular localization:	Nucleus .
Background:	The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using Fos B Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Immunofluorescence analysis of HepG2 cells, using FosB Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from COS7 and Jurkat cells, using FosB Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).