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EOMES rabbit pAb
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ES2266
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50 µL $148.00
100 µL $248.00
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Overview

Product name: EOMES rabbit pAb
Reactivity: Human;Mouse
Alternative Names: EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 73kD
GeneID: 8320
Human Swiss-Prot No: O95936
Cellular localization: Nucleus .
Background: This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],