eEF2K rabbit pAb

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eEF2K rabbit pAb

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ES2228

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	eEF2K rabbit pAb
Reactivity:	Human;Rat
Alternative Names:	EEF2K; Eukaryotic elongation factor 2 kinase; eEF-2 kinase; eEF-2K; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human eEF2K. AA range:331-380
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	105kD
GeneID:	29904
Human Swiss-Prot No:	O00418
Cellular localization:	cytoplasm,cytosol,postsynaptic density,
Background:	This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using eEF2K Polyclonal Antibody diluted at 1:500
Western Blot analysis of HeLa cells using eEF2K Polyclonal Antibody diluted at 1:500
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using eEF2K Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HeLa cells, treated with serum 10% 15', using eEF2K Antibody. The lane on the right is blocked with the synthesized peptide.