DMGDH rabbit pAb

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DMGDH rabbit pAb

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ES2179

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	DMGDH rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	DMGDH; Dimethylglycine dehydrogenase; mitochondrial; ME2GLYDH
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human DMGDH. AA range:817-866
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	97kD
GeneID:	29958
Human Swiss-Prot No:	Q9UI17
Cellular localization:	Mitochondrion.
Background:	This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Western Blot analysis of various cells using DMGDH Polyclonal Antibody
Western blot analysis of lysates from HT-29 and A549 cells, using DMGDH Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HeLa cells using DMGDH antibody.
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).