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D4DR rabbit pAb
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ES2137
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50 µL $148.00
100 µL $248.00
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Overview

Product name: D4DR rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: DRD4; D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 receptor
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human DRD4. AA range:355-404
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 48kD
GeneID: 1815
Human Swiss-Prot No: P21917
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008],