CUG-BP1 rabbit pAb

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CUG-BP1 rabbit pAb

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ES2071

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	CUG-BP1 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	CELF1; BRUNOL2; CUGBP; CUGBP1; NAB50; CUGBP Elav-like family member 1; CELF-1; 50 kDa nuclear polyadenylated RNA-binding protein; Bruno-like protein 2; CUG triplet repeat RNA-binding protein 1; CUG-BP1; CUG-BP- and ETR-3-like factor 1; Dead
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human CELF-1. AA range:71-120
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	52kD
GeneID:	10658
Human Swiss-Prot No:	Q92879
Cellular localization:	Nucleus . Cytoplasm . RNA-binding activity is detected in both nuclear and cytoplasmic compartments.
Background:	CUGBP, Elav-like family member 1(CELF1) Homo sapiens Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using CUG-BP1 Polyclonal Antibody diluted at 1:500
Western blot analysis of lysates from HeLa and HepG2 cells, using CELF-1 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).