ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb

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ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb

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ES20012

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	Integrin alpha-IIb (GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2]
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	Synthesized peptide derived from human ITGA2B (light chain form 1, Cleaved-Gln891)
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	16 110kD
GeneID:	3674
Human Swiss-Prot No:	P08514
Cellular localization:	Membrane; Single-pass type I membrane protein.
Background:	This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],

Immunohistochemical analysis of paraffin-embedded human spleen. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).