CDC46 rabbit pAb

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CDC46 rabbit pAb

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ES1933

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	CDC46 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	MCM5; CDC46; DNA replication licensing factor MCM5; CDC46 homolog; P1-CDC46
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human MCM5. AA range:21-70
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	90kD
GeneID:	4174
Human Swiss-Prot No:	P33992
Cellular localization:	Nucleus . Chromosome . Cytoplasm, cytosol . Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. .
Background:	The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using CDC46 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western Blot analysis of HepG2 cells using CDC46 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Immunofluorescence analysis of HepG2 cells, using MCM5 Antibody. The picture on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using MCM5 Antibody. The picture on the right is blocked with the synthesized peptide.