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CB2 rabbit pAb
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ES1874
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CB2 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: CNR2; Cannabinoid receptor 2; CB-2; CB2; hCB2; CX5
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CNR2. AA range:191-240
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 33kD
GeneID: 1269
Human Swiss-Prot No: P34972
Cellular localization: Cell membrane; Multi-pass membrane protein. Cell projection, dendrite . Perikaryon . Localizes to apical dendrite of pyramidal neurons. .
Background: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008],