Products

Cadherin-18 rabbit pAb
One-click to copy product information
ES1823
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Cadherin-18 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: CDH18; CDH14; Cadherin-18; Cadherin-14
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CDH18. AA range:101-150
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 88kD
GeneID: 1016
Human Swiss-Prot No: Q13634
Cellular localization: Cell membrane; Single-pass type I membrane protein.
Background: This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014],