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Cacna2d4 rabbit pAb
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ES1821
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Cacna2d4 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CACNA2D4; Voltage-dependent calcium channel subunit alpha-2/delta-4; Voltage-gated calcium channel subunit alpha-2/delta-4
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CACNA2D4. AA range:548-597
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 130kD
GeneID: 93589
Human Swiss-Prot No: Q7Z3S7
Cellular localization: Membrane ; Single-pass type I membrane protein .
Background: calcium voltage-gated channel auxiliary subunit alpha2delta 4(CACNA2D4) Homo sapiens This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],