BRMS-1 rabbit pAb

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BRMS-1 rabbit pAb

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ES1791

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	BRMS-1 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	BRMS1; Breast cancer metastasis-suppressor 1
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human BRMS1. AA range:21-70
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	28kD
GeneID:	25855
Human Swiss-Prot No:	Q9HCU9
Cellular localization:	Nucleus. Cytoplasm. Predominantly nuclear.
Background:	This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using BRMS-1 Polyclonal Antibody
Western blot analysis of lysates from 293 cells, using BRMS1 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4° overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).