Blk rabbit pAb

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Blk rabbit pAb

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ES1772

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Blk rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk
Source:	Rabbit
Dilutions:	Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human BLK. AA range:456-505
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	58kD
GeneID:	640
Human Swiss-Prot No:	P51451
Cellular localization:	Cell membrane ; Lipid-anchor . Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity). .
Background:	This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],

Western Blot analysis of various cells using Blk Polyclonal Antibody diluted at 1:500
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).