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Arginase II rabbit pAb
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ES1695
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Arginase II rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: ARG2; Arginase-2; mitochondrial; Kidney-type arginase; Non-hepatic arginase; Type II arginase
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human ARG2. AA range:305-354
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 384
Human Swiss-Prot No: P78540
Cellular localization: Mitochondrion .
Background: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008],