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Paxillin (phospho Tyr88) rabbit pAb
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ES1394
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Paxillin (phospho Tyr88) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: PXN; Paxillin
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Paxillin (phospho Tyr88)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 68kD
GeneID: 5829
Human Swiss-Prot No: P49023
Cellular localization: Cytoplasm, cytoskeleton . Cell junction, focal adhesion . Cytoplasm, cell cortex . Colocalizes with integrins at the cell periphery. Colocalize with PXN to membrane ruffles and the leading edge of migrating cells (PubMed:23128389). .
Background: This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011],