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Dok-2 (phospho Tyr299) rabbit pAb
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ES1299
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Dok-2 (phospho Tyr299) rabbit pAb
Reactivity: Human;Mouse;Monkey
Alternative Names: DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2)
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human p56 Dok-2 around the phosphorylation site of Tyr299. AA range:266-315
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 48kD
GeneID: 9046
Human Swiss-Prot No: O60496
Cellular localization: cytosol,
Background: docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],