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NANO2 rabbit pAb
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ES11270
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50 µL $148.00
100 µL $248.00
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Overview

Product name: NANO2 rabbit pAb
Reactivity: Human;Mouse
Source: Rabbit
Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 10-90
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 15kD
GeneID: 339345
Human Swiss-Prot No: P60321
Cellular localization: Cytoplasm . Cytoplasm, P-body . Cytoplasm, perinuclear region . Localizes at P-bodies during gonocyte development (By similarity). More abundant in perinuclear region of the cytoplasm of the germ cells of the adult testis. .
Background: domain:The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein.,function:Required to support proliferation and self-renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3'-UTR of mRNA targets. Essential for spermatogonia formation.,similarity:Belongs to the nanos family.,similarity:Contains 1 nanos-type zinc finger.,