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BD1L1 rabbit pAb
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ES10054
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50 µL $148.00
100 µL $248.00
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Overview

Product name: BD1L1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilutions: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human protein . at AA range: 1280-1360
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 335kD
GeneID: 259282
Human Swiss-Prot No: Q8NFC6
Cellular localization: Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. .
Background: Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM.