|Recombinant Human FKBP4 (C-6His)
|Recombinant Human 52 kDa FK506 Binding Protein is produced by our E.coli expression system and the target gene encoding Met1-Ala459 is expressed with a 6His tag at the C-terminus.
|Apparent molecular weight:
|50-60 KDa, reducing conditions
|Greater than 95% as determined by reducing SDS-PAGE.
|Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
|Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
|The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
|FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.