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ATG5 (3C7) Mouse mAb
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EM1374
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ATG5 (3C7) Mouse mAb
Reactivity: Human, Mouse, Rat
Alternative Names: APG5, APG5L, ASP, Autophagy protein 5 antibody
Source: Mouse
Dilutions: WB  1:5,000-10,000 IHC 1:100-200
Immunogen: Recombinant Protein
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed Band: 55kDa
GeneID: 9494
Human Swiss-Prot No: Q9H1Y0
Cellular localization: Cytoplasm, Membrane
Background: Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.