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P44/42 MAPK(ERK1/2) Mouse mAb
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EM1221
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50 µL $148.00
100 µL $248.00
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Overview

Product name: P44/42 MAPK(ERK1/2) Mouse mAb
Reactivity: Human, Rat, Mouse
Alternative Names: MAPK, Mitogen-activated protein Kinase, PRKM2,MK01
Source: Mouse
Dilutions: WB 1:1,000-2,000     IHC  1:100-200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed Band: 44,42kDa
GeneID: 5594/5595
Human Swiss-Prot No: P27361/P28482
Cellular localization: Nucleus
Background: Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.