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IDE/Insulin Degrading Enzyme Mouse mAb
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EM1083
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50 µL $148.00
100 µL $248.00
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Overview

Product name: IDE/Insulin Degrading Enzyme Mouse mAb
Reactivity: Human
Alternative Names: Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN
Source: Mouse
Dilutions: WB 1:1,000 IHC 1:200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed Band: 118kDa
GeneID: 3416
Human Swiss-Prot No: P14735
Cellular localization: Cell membrane, Cytoplasm, Membrane, Secreted
Background: Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.