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CDX2 Mouse mAb
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EM1057
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CDX2 Mouse mAb
Reactivity: Human, Rat, Mouse
Alternative Names: Caudal Type Homeobox Transcription Factor 2 ;CDX3; Homeobox Protein CDX-2
Source: Mouse
Dilutions: WB 1:1,000 IHC 1:200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed Band: 42kDa
GeneID: 1045
Human Swiss-Prot No: Q99626
Cellular localization: Nucleus
Background: CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.