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Calnexin Rabbit pAb
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EA214
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Calnexin Rabbit pAb
Reactivity: Human, Rat, Mouse
Alternative Names: CANX antibody, CNX antibody, FLJ26570 antibody, IP90 antibody, P90 antibody
Source: Rabbit
Dilutions: WB 1:1,000-2,000   IHC 1:200-500
Immunogen: Recombinant Protein
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed Band: 75,80,90kDa
GeneID: 821
Human Swiss-Prot No: P27824
Cellular localization: Endoplasmic reticulum membrane,Melanosome.
Background: Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail.