$148.00/50µL $248.00/100µL
50 µL | $148.00 |
100 µL | $248.00 |
Product name: | IκB α Rabbit pAb |
Reactivity: | Human, Rat |
Alternative Names: | I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody |
Source: | Rabbit |
Dilutions: | WB 1:2,000-5,000 IHC 1:200-500 |
Immunogen: | Recombinant Protein |
Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1mg/mL |
Observed Band: | 40kDa |
GeneID: | 4792 |
Human Swiss-Prot No: | P25963 |
Cellular localization: | Cytoplasm,Nucleus |
Background: | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. |