Product name: |
NEUR3 rabbit pAb |
Reactivity: |
Human; Mouse;Rat |
Source: |
Rabbit |
Dilutions: |
WB 1:500-2000 |
Immunogen: |
Synthesized peptide derived from human NEUR3 AA range: 132-182 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Molecular Weight: |
47kD |
Human Swiss-Prot No: |
Q9UQ49 |
Cellular localization: |
Cell membrane ; Peripheral membrane protein . Membrane, caveola . Early endosome membrane ; Peripheral membrane protein . Recycling endosome membrane ; Peripheral membrane protein . Lysosome membrane ; Peripheral membrane protein . Associates with the external leaflet of the plasma membrane (By similarity). S-acylated NEU3 likely spans the lipid bilayer with a portion of C-terminus exposed to the cytosol and the catalytic region facing the extracellular space (PubMed:28646141). . |
Background: |
This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer. [provided by RefSeq, Jul 2008], |