| Product name: |
NBR1 (7C3) Mouse mAb |
| Reactivity: |
Human, Mouse, Rat |
| Alternative Names: |
1A13B, MIG19, Nbr1 |
| Source: |
Mouse |
| Dilutions: |
IHC 1:100-200 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
120kDa |
| GeneID: |
4077 |
| Human Swiss-Prot No: |
Q14596 |
| Cellular localization: |
Cytoplasm, Cytoplasmic vesicle, Lysosome |
| Background: |
NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62. |
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