| Product name: |
Lamin B1 Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218 |
| Source: |
Mouse |
| Dilutions: |
WB 1:2,000-5,000 IP 1:200 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
68kDa |
| GeneID: |
4001 |
| Human Swiss-Prot No: |
P20700 |
| Cellular localization: |
Mitochondrion inner membrane |
| Background: |
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. |
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