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NBR1 (7C3) Mouse mAb
EM1373
Specification: Price:
50 µl $148.00
100 µl $248.00

Overview

Product name: NBR1 (7C3) Mouse mAb
Reactivity: Human, Mouse, Rat
Alternative Names: 1A13B, MIG19, Nbr1
Source: Mouse
Applications: IHC
Species: Human
Recommended dilutions: IHC 1:100-200
Immunogen: Recombinant Protein
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/ml
Observed band: 120kDa
GeneID(Human): 4077
Human Swiss-Prot No: Q14596
Cellular localization: Cytoplasm, Cytoplasmic vesicle, Lysosome
Background: NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.